Fatty acid metabolic reprogramming via mTOR-mediated inductions of PPARγ directs early activation of T cells
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/ncomms13683.pdf
Reference49 articles.
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3. Colombetti, S., Basso, V., Mueller, D. L. & Mondino, A. Prolonged TCR/CD28 engagement drives IL-2-independent T cell clonal expansion through signaling mediated by the mammalian target of rapamycin. J. Immunol. 176, 2730–2738 (2006).
4. Mondino, A. & Mueller, D. L. mTOR at the crossroads of T cell proliferation and tolerance. Semin. Immunol. 19, 162–172 (2007).
5. Chi, H. Regulation and function of mTOR signalling in T cell fate decisions. Nat. Rev. Immunol. 12, 325–338 (2012).
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