ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A-Reference-Cited by-同舟云学术

ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A

Published:2016-12 Issue:1 Volume:7 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Williamson Chris T.,Miller Rowan,Pemberton Helen N.,Jones Samuel E.,Campbell James,Konde Asha,Badham Nicholas,Rafiq Rumana,Brough Rachel,Gulati Aditi,Ryan Colm J.^ORCID,Francis Jeff,Vermulen Peter B.,Reynolds Andrew R.,Reaper Philip M.,Pollard John R.,Ashworth Alan,Lord Christopher J.

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/ncomms13837.pdf

Reference47 articles.

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3. Moynahan, M. E. & Jasin, M. Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis. Nat. Rev. Mol. Cell Biol. 11, 196–207 (2010).

4. Zeman, M. K. & Cimprich, K. A. Causes and consequences of replication stress. Nat. Cell Biol. 16, 2–9 (2014).

5. Karnitz, L. M. & Zou, L. Molecular pathways: targeting ATR in cancer therapy. Clin. Cancer Res. 21, 4780–4785 (2015).

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