Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories-Reference-Cited by-同舟云学术

Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories

Published:2017-01-09 Issue:1 Volume:8 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Taylor Renea A.,Fraser Michael,Livingstone Julie^ORCID,Espiritu Shadrielle Melijah G.,Thorne Heather,Huang Vincent^ORCID,Lo Winnie,Shiah Yu-Jia,Yamaguchi Takafumi N.^ORCID,Sliwinski Ania,Horsburgh Sheri,Meng Alice,Heisler Lawrence E.,Yu Nancy,Yousif Fouad,Papargiris Melissa,Lawrence Mitchell G.,Timms Lee,Murphy Declan G.,Frydenberg Mark,Hopkins Julia F.,Bolton Damien,Clouston David,McPherson John D.,van der Kwast Theodorus,Boutros Paul C.^ORCID,Risbridger Gail P.,Bristow Robert G.

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/ncomms13671.pdf

Reference56 articles.

1. Castro, E. et al. Effect of BRCA mutations on metastatic relapse and cause-specific survival after radical treatment for localised prostate cancer. Eur. Urol. 68, 186–193 (2015).

2. Willems, A. J. et al. Loss of heterozygosity at the BRCA2 locus detected by multiplex ligation-dependent probe amplification is common in prostate cancers from men with a germline BRCA2 mutation. Clin. Cancer Res. 14, 2953–2961 (2008).

3. Akbari, M. R. et al. The impact of a BRCA2 mutation on mortality from screen-detected prostate cancer. Br. J. Cancer 111, 1238–1240 (2014).

4. Castro, E. et al. Germline BRCA mutations are associated with higher risk of nodal involvement, distant metastasis, and poor survival outcomes in prostate cancer. J. Clin. Oncol. 31, 1748–1757 (2013).

5. Risbridger, G. P. et al. Patient-derived xenografts reveal that intraductal carcinoma of the prostate is a prominent pathology in BRCA2 mutation carriers with prostate cancer and correlates with poor prognosis. Eur. Urol. 67, 496–503 (2015).

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