A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/ncomms13781.pdf
Reference55 articles.
1. El-Serag, H. B. Hepatocellular carcinoma. N. Engl. J. Med. 365, 1118–1127 (2011).
2. Pinyol, R., Nault, J. C., Quetglas, I. M., Zucman-Rossi, J. & Llovet, J. M. Molecular profiling of liver tumors: classification and clinical translation for decision making. Semin. Liver Dis. 34, 363–375 (2014).
3. Yimlamai, D., Fowl, B. H. & Camargo, F. D. Emerging evidence on the role of the Hippo/YAP pathway in liver physiology and cancer. J. Hepatol. 63, 1491–1501 (2015).
4. Pilati, C. et al. Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas. J. Exp. Med. 208, 1359–1366 (2011).
5. Schulze, K. et al. Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets. Nat. Genet. 47, 505–511 (2015).
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