Tesofensine, a Novel Triple Monoamine Reuptake Inhibitor, Induces Appetite Suppression by Indirect Stimulation of α1 Adrenoceptor and Dopamine D1 Receptor Pathways in the Diet-Induced Obese Rat
Author:
Publisher
Springer Science and Business Media LLC
Subject
Psychiatry and Mental health,Pharmacology
Link
http://www.nature.com/articles/npp201016.pdf
Reference56 articles.
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3. Astrup A, Meier DH, Mikkelsen BO, Villumsen JS, Larsen TM (2008b). Weight loss produced by tesofensine in patients with Parkinson′s or Alzheimer′s disease. Obesity (Silver Spring) 16: 1363–1369.
4. Balcioglu A, Wurtman RJ (2000). Sibutramine, a serotonin uptake inhibitor, increases dopamine concentrations in rat striatal and hypothalamic extracellular fluid. Neuropharmacology 39: 2352–2359.
5. Billes SK, Cowley MA (2007). Inhibition of dopamine and norepinephrine reuptake produces additive effects on energy balance in lean and obese mice. Neuropsychopharmacology 32: 822–834.
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