Activation of the p53 pathway by the MDM2 inhibitor nutlin-3a overcomes BCL2 overexpression in a preclinical model of diffuse large B-cell lymphoma associated with t(14;18)(q32;q21)

Author:

Drakos E,Singh R R,Rassidakis G Z,Schlette E,Li J,Claret F X,Ford R J,Vega F,Medeiros L J

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Cancer Research,Hematology

Reference51 articles.

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2. Stein H, Chan JKC, Warnke RA, Gatter KC, Chan WC, Campo E et al. Diffuse large B-cell lymphoma, not otherwise specified. In: Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW (eds). World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues, (4th edn) IARC Press: Lyon, France, 2008, 233–237.

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4. McDonnell TJ, Deane N, Platt FM, Nunez G, Jaeger U, McKearn JP et al. bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation. Cell 1989; 57: 79–88.

5. Hollstein M, Sidransky D, Vogelstein B, Harris CC . p53 mutations in human cancers. Science 1991; 253: 49–53.

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