Wnt signaling strength regulates normal hematopoiesis and its deregulation is involved in leukemia development
Author:
Publisher
Springer Science and Business Media LLC
Subject
Oncology,Cancer Research,Hematology
Link
http://www.nature.com/articles/leu2011387.pdf
Reference78 articles.
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2. Malhotra S, Kincade PW . Wnt-related molecules and signaling pathway equilibrium in hematopoiesis. Cell Stem Cell 2009; 4: 27–36.
3. Barker N, Clevers H . Leucine-rich repeat-containing G-protein-coupled receptors as markers of adult stem cells. Gastroenterology 2010; 138: 1681–1696.
4. Carmon KS, Gong X, Lin Q, Thomas A, Liu Q . R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling. Proc Natl Acad Sci USA 2011; 108: 11452–11457.
5. Staal FJ, Sen JM . The canonical Wnt signaling pathway plays an important role in lymphopoiesis and hematopoiesis. Eur J Immunol 2008; 38: 1788–1794.
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