Perampanel—new promise for refractory epilepsy?
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cellular and Molecular Neuroscience,Neurology (clinical)
Link
http://www.nature.com/articles/nrneurol.2012.222.pdf
Reference10 articles.
1. Löscher, W. & Schmidt, D. Modern antiepileptic drug development has failed to deliver: ways out of the current dilemma. Epilepsia 52, 657–678 (2011).
2. Beyenburg, S., Stavem, K. & Schmidt, D. Placebo-corrected efficacy of modern antiepileptic drugs for refractory epilepsy: systematic review and meta-analysis. Epilepsia 51, 7–26 (2010).
3. French, J. A. et al. Adjunctive perampanel for refractory partial-onset seizures: randomized phase III study 304. Neurology 79, 589–596 (2012).
4. French, J. A. et al. Evaluation of adjunctive perampanel in patients with refractory partial-onset seizures: results of randomized global phase III study 305. Epilepsia http://dx.doi.org/10.1111/j.1528-1167.2012.03638.x .
5. Krauss, G. L. et al. Randomized phase III study 306: adjunctive perampanel for refractory partial-onset seizures. Neurology 78, 1408–1415 (2012).
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