Immunotherapy for Alzheimer disease—the challenge of adverse effects-Reference-Cited by-同舟云学术

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Immunotherapy for Alzheimer disease—the challenge of adverse effects

Published:2012-07-03 Issue:8 Volume:8 Page:465-469
ISSN:1759-4758
Container-title:Nature Reviews Neurology
language:en
Short-container-title:Nat Rev Neurol

Author:

Liu Yu-Hui,Giunta Brian,Zhou Hua-Dong,Tan Jun,Wang Yan-Jiang

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Clinical Neurology

Link

http://www.nature.com/articles/nrneurol.2012.118.pdf

Reference41 articles.

1. Hardy, J. & Selkoe, D. J. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297, 353–356 (2002).

2. Holmes, C. et al. Long-term effects of Aβ42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial. Lancet 372, 216–223 (2008).

3. Salloway, S. et al. A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease. Neurology 73, 2061–2070 (2009).

4. Gilman, S. et al. Clinical effects of Aβ immunization (AN1792) in patients with AD in an interrupted trial. Neurology 64, 1553–1562 (2005).

5. Hyman, B. T. Amyloid-dependent and amyloid-independent stages of Alzheimer disease. Arch. Neurol. 68, 1062–1064 (2011).

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