A chimeric fusion of the hASH1 and EZH2 promoters mediates high and specific reporter and suicide gene expression and cytotoxicity in small cell lung cancer cells

Author:

Poulsen T T,Pedersen N,Juel H,Poulsen H S

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Molecular Biology,Molecular Medicine

Reference47 articles.

1. Ciombor KK, Rocha Lima CM . Management of small cell lung cancer. Curr Treat Options Oncol 2006; 7: 59–68.

2. Poulsen TT, Pedersen N, Poulsen HS . Replacement and suicide gene therapy for targeted treatment of lung cancer. Clin Lung Cancer 2005; 6: 227–236.

3. Moolten FL . Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy. Cancer Res 1986; 46: 5276–5281.

4. Fillat C, Carrio M, Cascante A, Sangro B . Suicide gene therapy mediated by the herpes simplex virus thymidine kinase gene/ganciclovir system: fifteen years of application. Curr Gene Ther 2003; 3: 13–26.

5. Tanaka M, Inase N, Miyake S, Yoshizawa Y . Neuron specific enolase promoter for suicide gene therapy in small cell lung carcinoma. Anticancer Res 2001; 21: 291–294.

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