Tissue-type plasminogen activator has antiangiogenic properties without effect on tumor growth in a rat C6 glioma model-Reference-Cited by-同舟云学术

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Tissue-type plasminogen activator has antiangiogenic properties without effect on tumor growth in a rat C6 glioma model

Published:2008-06-06 Issue:10 Volume:15 Page:685-692
ISSN:0929-1903
Container-title:Cancer Gene Therapy
language:en
Short-container-title:Cancer Gene Ther

Author:

Solly F,Fish R,Simard B,Bolle N,Kruithof E,Polack B,Pernod G

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Molecular Biology,Molecular Medicine

Link

http://www.nature.com/articles/cgt200836.pdf

Reference34 articles.

1. O'Reilly MS, Holmgren L, Shing Y, Chen C, Rosenthal RA, Moses M et al. Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 1994; 79: 315–328.

2. Gately S, Twardowski P, Stack MS, Cundiff DL, Grella D, Castellino FJ et al. The mechanism of cancer-mediated conversion of plasminogen to the angiogenesis inhibitor angiostatin. Proc Natl Acad Sci USA 1997; 94: 10868–10872.

3. Stathakis P, Fitzgerald M, Matthias LJ, Chesterman CN, Hogg PJ . Generation of angiostatin by reduction and proteolysis of plasmin. Catalysis by a plasmin reductase secreted by cultured cells. J Biol Chem 1997; 272: 20641–20645.

4. Stathakis P, Lay AJ, Fitzgerald M, Schlieker C, Matthias LJ, Hogg PJ . Angiostatin formation involves disulfide bond reduction and proteolysis in kringle 5 of plasmin. J Biol Chem 1999; 274: 8910–8916.

5. Geiger JH, Cnudde SE . What the structure of angiostatin may tell us about its mechanism of action. J Thromb Haemost 2004; 2: 23–34.

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