Alzheimer risk factors age and female sex induce cortical Aβ aggregation by raising extracellular zinc
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cellular and Molecular Neuroscience,Psychiatry and Mental health,Molecular Biology
Link
http://www.nature.com/articles/s41380-020-0800-y.pdf
Reference82 articles.
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2. Callahan MJ, Lipinski WJ, Bian F, Durham RA, Pack A, Walker LC. Augmented senile plaque load in aged female beta-amyloid precursor protein-transgenic mice. Am J Pathol. 2001;158:1173–7.
3. Corder EH, Ghebremedhin E, Taylor MG, Thal DR, Ohm TG, Braak H. The biphasic relationship between regional brain senile plaque and neurofibrillary tangle distributions: modification by age, sex, and APOE polymorphism. Ann NY Acad Sci. 2004;1019:24–8.
4. Lee J-Y, Cole TB, Palmiter RD, Suh SW, Koh J-Y. Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice. Proc Natl Acad Sci USA. 2002;99:7705–10.
5. Takeda A, Tamano H, Tempaku M, Sasaki M, Uematsu C, Sato S, et al. Extracellular Zn(2+) is essential for amyloid beta1-42-induced cognitive decline in the normal brain and its rescue. J Neurosci. 2017;37:7253–62.
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