Repurposing antidepressants inhibiting the sphingomyelinase acid/ceramide system against COVID-19: current evidence and potential mechanisms
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cellular and Molecular Neuroscience,Psychiatry and Mental health,Molecular Biology
Link
https://www.nature.com/articles/s41380-021-01254-3.pdf
Reference16 articles.
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2. Stip E, Arnone D, Abdel Aziz K, Javaid S. Diversity of mechanism of action of psychotropic drugs in their anti-COVID-19 properties. Mol Psychiatry. 2021:1–5. https://doi.org/10.1038/s41380-021-01222-x. Epub ahead of print.
3. Hoertel N, Sánchez-Rico M, Vernet R, Beeker N, Jannot A-S, Neuraz A, et al. Association between antidepressant use and reduced risk of intubation or death in hospitalized patients with COVID-19: results from an observational study. Mol Psychiatry. 2021. https://doi.org/10.1038/s41380-021-01021-4 Epub ahead of print.
4. Hoertel N, Sánchez-Rico M, Vernet R, Beeker N, Jannot A-S, Neuraz A, et al. SSRIs and SNRIs and Risk of Death or Intubation in COVID-19: Results from an Observational Study. medRxiv 2020.07.09.20143339; https://doi.org/10.1101/2020.07.09.20143339.
5. Kornhuber J, Tripal P, Reichel M, Mühle C, Rhein C, Muehlbacher M, et al. Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): a novel pharmacological group of drugs with broad clinical applications. Cell Physiol Biochem. 2010;26:9–20.
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