GLP-1 receptor signaling in the laterodorsal tegmental nucleus attenuates cocaine seeking by activating GABAergic circuits that project to the VTA

Author:

Hernandez Nicole S.,Weir Vanessa R.ORCID,Ragnini Kael,Merkel Riley,Zhang Yafang,Mace Kyla,Rich Matthew T.,Christopher Pierce R.,Schmidt Heath D.ORCID

Funder

U.S. Department of Health & Human Services | NIH | National Institute on Drug Abuse

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Psychiatry and Mental health,Molecular Biology

Reference62 articles.

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2. Hughes A, Williams MR, Lipari RN, Van Horn S. State estimates of past year cocaine use among young adults: 2014 and 2015. Report TC. Rockville, MD: Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration; 2016.

3. Pierce RC, O’Brien CP, Kenny PJ, Vanderschuren LJ. Rational development of addiction pharmacotherapies: successes, failures, and prospects. Cold Spring Harb Perspect Med. 2012;2:a012880.

4. Graham DL, Erreger K, Galli A, Stanwood GD. GLP-1 analog attenuates cocaine reward. Mol Psychiatry. 2013;18:961–2.

5. Sorensen G, Reddy IA, Weikop P, Graham DL, Stanwood GD, Wortwein G, et al. The glucagon-like peptide 1 (GLP-1) receptor agonist exendin-4 reduces cocaine self-administration in mice. Physiol Behav. 2015;149:262–8.

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