Chromatin architecture in addiction circuitry identifies risk genes and potential biological mechanisms underlying cigarette smoking and alcohol use traits

Author:

Sey Nancy Y. A.,Hu Benxia,Iskhakova MarinaORCID,Lee SoolORCID,Sun Huaigu,Shokrian Neda,Ben Hutta Gabriella,Marks Jesse A.ORCID,Quach Bryan C.ORCID,Johnson Eric O.ORCID,Hancock Dana B.ORCID,Akbarian SchahramORCID,Won HyejungORCID

Funder

U.S. Department of Health & Human Services | NIH | National Institute on Drug Abuse

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health

National Science Foundation

Howard Hughes Medical Institute

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Psychiatry and Mental health,Molecular Biology

Reference70 articles.

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2. Peacock A, Leung J, Larney S, Colledge S, Hickman M, Rehm J, et al. Global statistics on alcohol, tobacco and illicit drug use: 2017 status report. Addiction. 2018;113:1905–26.

3. National Center for Chronic Disease Prevention and Health Promotion (US) Office on Smoking and Health. The Health Consequences of Smoking—50 Years of Progress: A Report of the Surgeon General. Atlanta (GA): Centers for Disease Control and Prevention (US); 2014.

4. Kranzler HR, Zhou H, Kember RL, Vickers Smith R, Justice AC, Damrauer S, et al. Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations. Nat Commun. 2019;10:1499.

5. Liu M, Jiang Y, Wedow R, Li Y, Brazel DM, Chen F, et al. Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use. Nat Genet. 2019;51:237–44.

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