Evaluation of the safety, pharmacokinetics and pharmacodynamic effects of subcutaneously administered PT-141, a melanocortin receptor agonist, in healthy male subjects and in patients with an inadequate response to Viagra®-Reference-Cited by-同舟云学术

Evaluation of the safety, pharmacokinetics and pharmacodynamic effects of subcutaneously administered PT-141, a melanocortin receptor agonist, in healthy male subjects and in patients with an inadequate response to Viagra®

Published:2004-03-04 Issue:2 Volume:16 Page:135-142
ISSN:0955-9930
Container-title:International Journal of Impotence Research
language:en
Short-container-title:Int J Impot Res

Author:

Rosen R C,Diamond L E,Earle D C,Shadiack A M,Molinoff P B

Publisher

Springer Science and Business Media LLC

Subject

Urology

Link

http://www.nature.com/articles/3901200.pdf

Reference22 articles.

1. Lue TF . Erectile dysfunction. N Engl J Med 2000; 342: 1802–1813.

2. Goldstein I et al. Oral sildenafil in the treatment of erectile dysfunction. N Engl J Med 1998; 338: 1397–1404.

3. Porst H et al. The efficacy and tolerability of Vardenafil, a new, oral, selective phosphodiesterase type 5 inhibitor, in patients with erectile dysfunction: the first at-home clinical trial. Int J Impot Res 2001; 13: 192–199.

4. Padma-Nathan H et al. On-demand IC351 (Cialis™) enhances erectile function in patients with erectile dysfunction. Int J Impot Res 2001; 13: 2–9.

5. Padma-Nathan H, Steers WD, Wicker PA . Efficacy and safety of oral sildenafil in the treatment of erectile dysfunction: a double-blind, placebo-controlled study of 329 patients. Int J Clin Pract 1998; 52: 375–379.

Cited by 73 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A review on pharmacological options for the treatment of erectile dysfunction: state of the art and new strategies;Expert Opinion on Pharmacotherapy;2023-06-10

2. Pro-resolving and anti-arthritic properties of the MC1 selective agonist PL8177;Frontiers in Immunology;2022-11-24

3. Pharmacokinetics of the Melanocortin Type 1 Receptor Agonist PL8177 After Subcutaneous Administration;Drugs in R&D;2021-10-25

4. The neurobiology of bremelanotide for the treatment of hypoactive sexual desire disorder in premenopausal women;CNS Spectrums;2021-01-18

5. Novel Emerging Therapies for Erectile Dysfunction;The World Journal of Men's Health;2021