Mapping recently identified nucleotide variants in the genome and transcriptome-Reference-Cited by-同舟云学术

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Mapping recently identified nucleotide variants in the genome and transcriptome

Published:2012-11 Issue:11 Volume:30 Page:1107-1116
ISSN:1087-0156
Container-title:Nature Biotechnology
language:en
Short-container-title:Nat Biotechnol

Author:

Song Chun-Xiao,Yi Chengqi,He Chuan

Publisher

Springer Science and Business Media LLC

Subject

Biomedical Engineering,Molecular Medicine,Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

http://www.nature.com/articles/nbt.2398.pdf

Reference123 articles.

1. Klose, R.J. & Bird, A.P. Genomic DNA methylation: the mark and its mediators. Trends Biochem. Sci. 31, 89–97 (2006).

2. Jones, P.A. Functions of DNA methylation: islands, start sites, gene bodies and beyond. Nat. Rev. Genet. 13, 484–492 (2012).

3. Kriaucionis, S. & Heintz, N. The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science 324, 929–930 (2009). Authors show that 5hmC is present in high levels in Purkinje cells, suggesting a role for 5hmC in neuronal function.

4. Tahiliani, M. et al. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 324, 930–935 (2009). This paper showed that 5hmC is present in ESCs and is enzymatically produced through TET-catalyzed oxidation of 5mC.

5. Pfaffeneder, T. et al. The discovery of 5-formylcytosine in embryonic stem cell DNA. Angew. Chem. Int. Ed. Engl. 50, 7008–7012 (2011).

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