Insights into antifolate resistance from malarial DHFR-TS structures-Reference-Cited by-同舟云学术

Insights into antifolate resistance from malarial DHFR-TS structures

Published:2003-04-21 Issue:5 Volume:10 Page:357-365
ISSN:1545-9993
Container-title:Nature Structural & Molecular Biology
language:en
Short-container-title:Nat Struct Mol Biol

Author:

Yuvaniyama Jirundon,Chitnumsub Penchit,Kamchonwongpaisan Sumalee,Vanichtanankul Jarunee,Sirawaraporn Worachart,Taylor Paul,Walkinshaw Malcolm D.,Yuthavong Yongyuth

Publisher

Springer Science and Business Media LLC

Subject

Molecular Biology,Structural Biology

Link

http://www.nature.com/articles/nsb921.pdf

Reference57 articles.

1. Breman, J.G. The ears of the hippopotamus: manifestations, determinants, and estimates of the malaria burden. Am. J. Trop. Med. Hyg. 64, 1–11 (2001).

2. Ferone, R. Folate metabolism in malaria. Bull. World Health Organ. 55, 291–298 (1977).

3. Cowman, A.F., Morry, M.J., Biggs, B.A., Cross, G.A.M. & Foote, S.J. Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase–thymidylate synthase gene of Plasmodium falciparum. Proc. Natl. Acad. Sci. USA 85, 9109–9113 (1988).

4. Peterson, D.S., Walliker, D. & Wellems, T.E. Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria. Proc. Natl. Acad. Sci. USA 85, 9114–9118 (1988).

5. Foote, S.J., Galatis, D. & Cowman, A.F. Amino acids in the dihydrofolate reductase–thymidylate synthase gene of Plasmodium falciparum involved in cycloguanil resistance differ from those involved in pyrimethamine resistance. Proc. Natl. Acad. Sci. USA 87, 3014–3017 (1990).

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