Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.nature.com/articles/s41573-019-0016-5.pdf
Reference289 articles.
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3. Le Floc’h, N., Otten, W. & Merlot, E. Tryptophan metabolism, from nutrition to potential therapeutic applications. Amino Acids 41, 1195–1205 (2011).
4. Stone, T. W., Stoy, N. & Darlington, L. G. An expanding range of targets for kynurenine metabolites of tryptophan. Trends Pharmacol. Sci. 34, 136–143 (2013).
5. van der Goot, A. T. & Nollen, E. A. Tryptophan metabolism: entering the field of aging and age-related pathologies. Trends Mol. Med. 19, 336–344 (2013).
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