3D Mass Spectrometry Imaging Reveals a Very Heterogeneous Drug Distribution in Tumors-Reference-Cited by-同舟云学术

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3D Mass Spectrometry Imaging Reveals a Very Heterogeneous Drug Distribution in Tumors

Published:2016-11-14 Issue:1 Volume:6 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Giordano S.,Morosi L.,Veglianese P.,Licandro S. A.,Frapolli R.,Zucchetti M.,Cappelletti G.,Falciola L.,Pifferi V.,Visentin S.,D’Incalci M.,Davoli E.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep37027.pdf

Reference44 articles.

1. Tredan, O., Galmarini, C. M., Patel, K. & Tannock, I. F. Drug resistance and the solid tumor microenvironment. J Natl Cancer Inst. 99, 1441–1454 (2007).

2. Hata, A. N. et al. Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition. Nat Med. 22, 262–269 (2016).

3. Bielenberg, D. R. & Zetter, B. R. The Contribution of Angiogenesis to the Process of Metastasis. Cancer J. 21, 267–273 (2015).

4. Solyanik, G. I. Multifactorial nature of tumor drug resistance. Exp Oncol. 32, 181–185 (2010).

5. Fuso Nerini, I. et al. Intratumor heterogeneity and its impact on drug distribution and sensitivity. Clin Pharmacol Ther. 96, 224–238 (2014).

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