New approaches for dissecting protease functions to improve probe development and drug discovery
Author:
Publisher
Springer Science and Business Media LLC
Subject
Molecular Biology,Structural Biology
Link
http://www.nature.com/articles/nsmb.2203.pdf
Reference93 articles.
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3. Powers, J.C., Asgian, J.L., Ekici, O.D. & James, K.E. Irreversible inhibitors of serine, cysteine, and threonine proteases. Chem. Rev. 102, 4639–4750 (2002).
4. Johnson, S.L. & Pellecchia, M. Structure- and fragment-based approaches to protease inhibition. Curr. Top. Med. Chem. 6, 317–329 (2006).
5. Turk, B. Targeting proteases: successes, failures and future prospects. Nat. Rev. Drug Discov. 5, 785–799 (2006).
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