High throughput cell-based assay for identification of glycolate oxidase inhibitors as a potential treatment for Primary Hyperoxaluria Type 1
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep34060.pdf
Reference41 articles.
1. Cochat, P. et al. Primary hyperoxaluria Type 1: indications for screening and guidance for diagnosis and treatment. Nephrol Dial Transplant 27, 1729–1736, doi: 10.1093/ndt/gfs078 (2012).
2. Oppici, E., Montioli, R. & Cellini, B. Liver peroxisomal alanine:glyoxylate aminotransferase and the effects of mutations associated with Primary Hyperoxaluria Type I: An overview. Biochim Biophys Acta 1854, 1212–1219, doi: 10.1016/j.bbapap.2014.12.029 (2015).
3. Lage, M. D., Pittman, A. M., Roncador, A., Cellini, B. & Tucker, C. L. Allele-specific characterization of alanine: glyoxylate aminotransferase variants associated with primary hyperoxaluria. PLoS One 9, e94338, doi: 10.1371/journal.pone.0094338 (2014).
4. Williams, E. L. et al. Primary hyperoxaluria type 1: update and additional mutation analysis of the AGXT gene. Hum Mutat 30, 910–917, doi: 10.1002/humu.21021 (2009).
5. Danpure, C. J., Cooper, P. J., Wise, P. J. & Jennings, P. R. An enzyme trafficking defect in two patients with primary hyperoxaluria type 1: peroxisomal alanine/glyoxylate aminotransferase rerouted to mitochondria. J Cell Biol 108, 1345–1352 (1989).
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