Transcriptional regulation of hepatic lipogenesis
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/nrm4074.pdf
Reference133 articles.
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3. Kemper, J. K., Choi, S. E. & Kim, D. H. Sirtuin 1 deacetylase: a key regulator of hepatic lipid metabolism. Vitam. Horm. 91, 385–404 (2013).
4. Viollet, B. et al. Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders. J. Physiol. 574, 41–53 (2006).
5. Wang, D. & Sul, H. S. Upstream stimulatory factor binding to the E-box at -65 is required for insulin regulation of the fatty acid synthase promoter. J. Biol. Chem. 272, 26367–26374 (1997). This work demonstrates that USF binding to the -65 E-box in the Fas promoter is required for transcriptional activation of the Fas gene by insulin.
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