Commonly used caspase inhibitors designed based on substrate specificity profiles lack selectivity
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/7310112.pdf
Reference9 articles.
1. Janicke RU, Sohn D, Totzke G, Schulze-Osthoff K . Caspase-10 in mouse or not? Science 2006; 312:1874.
2. Boatright KM, Renatus M, Scott FL, et al. A unified model for apical caspase activation. Mol Cell 2003; 11:529–541.
3. Pop C, Timmer J, Sperandio S, Salvesen GS . The apoptosome activates caspase-9 by dimerization. Mol Cell 2006; 22:269–275.
4. Denault JB, Bekes M, Scott FL, Sexton KM, Bogyo M, Salvesen GS . Engineered hybrid dimers: tracking the activation pathway of caspase-7. Mol Cell 2006; 23:523–533.
5. Berger AB, Witte MD, Denault JB, et al. Identification of early intermediates of caspase activation using selective inhibitors and activity-based probes. Mol Cell 2006; 23:509–521.
Cited by 102 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Caspase-8-mediated inflammation but not apoptosis drives death of retinal ganglion cells and loss of visual function in glaucomaa;2024-06-18
2. A Comprehensive Exploration of Caspase Detection Methods: From Classical Approaches to Cutting-Edge Innovations;International Journal of Molecular Sciences;2024-05-17
3. Inhibition of Apoptosis in a Model of Ischemic Stroke Leads to Enhanced Cell Survival, Endogenous Neural Precursor Cell Activation and Improved Functional Outcomes;International Journal of Molecular Sciences;2024-02-01
4. Development of Noninvasive Activity-Based Protein Profiling-Bioluminescence Resonance Energy Transfer Platform Technology Enables Target Engagement Studies with Absolute Specificity in Living Systems;ACS Pharmacology & Translational Science;2024-01-04
5. The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases;Cell Reports;2023-12
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3