Fusion transcripts are present in early progenitor cells in KMT2A-rearranged B-ALL
Author:
Funder
Kay Kendall Leukaemia Fund
RCUK | MRC | Medical Research Foundation
Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s41375-024-02164-3.pdf
Reference15 articles.
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3. Pieters R, De Lorenzo P, Ancliffe P, Aversa LA, Brethon B, Biondi A, et al. Outcome of infants younger than 1 year with acute lymphoblastic leukemia treated with the interfant-06 protocol: results from an international phase III Randomized Study. J Clin Oncol. 2019;37:2246–56.
4. Gardner R, Wu D, Cherian S, Fang M, Hanafi LA, Finney O, et al. Acquisition of a CD19-negative myeloid phenotype allows immune escape of MLL-rearranged B-ALL from CD19 CAR-T-cell therapy. Blood. 2016;127:2406–10.
5. Khabirova E, Jardine L, Coorens THH, Webb S, Treger TD, Engelbert J, et al. Single-cell transcriptomics reveals a distinct developmental state of KMT2A-rearranged infant B-cell acute lymphoblastic leukemia. Nat Med. 2022;28:743–51.
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