CD8+ CD28− regulatory T cells after induction therapy predict progression-free survival in myeloma patients: results from the GMMG-HD6 multicenter phase III study
Author:
Funder
Bristol-Myers Squibb
Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s41375-024-02290-y.pdf
Reference15 articles.
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2. Muthu Raja KR, Rihova L, Zahradova L, Klincova M, Penka M, Hajek R. Increased T regulatory cells are associated with adverse clinical features and predict progression in multiple myeloma. PloS One. 2012;7:e47077.
3. Collins SM, Bakan CE, Swartzel GD, Hofmeister CC, Efebera YA, Kwon H, et al. Elotuzumab directly enhances NK cell cytotoxicity against myeloma via CS1 ligation: evidence for augmented NK cell function complementing ADCC. Cancer Immunol, Immunother. 2013;62:1841–9.
4. Pazina T, James AM, Colby KB, Yang Y, Gale A, Jhatakia A, et al. Enhanced SLAMF7 homotypic interactions by elotuzumab improves NKcell killing of multiple myeloma. Cancer Immunol Res. 2019;7:1633–46.
5. MHS Awwad, A Mahmoud, H Bruns, H Echchannaoui, K Kriegsmann, R Lutz et al. Selective elimination of immunosuppressive T cells in patients with multiple myeloma. Leukemia. 2021;35:2602–2615.
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