The ENL YEATS epigenetic reader domain critically links MLL-ENL to leukemic stem cell frequency in t(11;19) Leukemia-Reference-Cited by-同舟云学术

The ENL YEATS epigenetic reader domain critically links MLL-ENL to leukemic stem cell frequency in t(11;19) Leukemia

Published:2022-11-26 Issue:1 Volume:37 Page:190-201
ISSN:0887-6924
Container-title:Leukemia
language:en
Short-container-title:Leukemia

Author:

Hu Hsiangyu,Saha Nirmalya,Yang Yuting,Ahmad Ejaz^ORCID,Lachowski Lauren,Shrestha Uttar,Premkumar Vidhya,Ropa James,Chen Lili,Teahan Blaine,Grigsby Sierrah^ORCID,Marschalek Rolf^ORCID,Nikolovska-Coleska Zaneta,Muntean Andrew G.^ORCID

Funder

U-M | MCubed, University of Michigan

Michigan Drug Discovery

U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute

U.S. Department of Health & Human Services | NIH | National Cancer Institute

Publisher

Springer Science and Business Media LLC

Subject

Computer Networks and Communications,Hardware and Architecture,Software

Link

https://www.nature.com/articles/s41375-022-01765-0.pdf

Reference56 articles.

1. Balgobind BV, Zwaan CM, Pieters R, Van den Heuvel-Eibrink MM. The heterogeneity of pediatric MLL-rearranged acute myeloid leukemia. Leukemia. 2011;25:1239–48.

2. Krivtsov AV, Armstrong SA. MLL translocations, histone modifications and leukaemia stem-cell development. Nat Rev Cancer. 2007;7:823–33.

3. Tkachuk DC, Kohler S, Cleary ML. Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias. Cell. 1992;71:691–700.

4. Winters AC, Bernt KM. MLL-rearranged leukemias-an update on science and clinical approaches. Front Pediatr. 2017;5:4.

5. Meyer C, Kowarz E, Hofmann J, Renneville A, Zuna J, Trka J, et al. New insights to the MLL recombinome of acute leukemias. Leukemia. 2009;23:1490–9.

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