GM-CSF disruption in CART cells modulates T cell activation and enhances CART cell anti-tumor activity-Reference-Cited by-同舟云学术

GM-CSF disruption in CART cells modulates T cell activation and enhances CART cell anti-tumor activity

Published:2022-04-19 Issue:6 Volume:36 Page:1635-1645
ISSN:0887-6924
Container-title:Leukemia
language:en
Short-container-title:Leukemia

Author:

Cox Michelle J.^ORCID,Manriquez Roman Claudia,Tapper Erin E.,Siegler Elizabeth L.,Chappell Dale,Durrant Cameron,Ahmed Omar,Sinha Sutapa,Mwangi Raphael,Scott Nancy S.,Hefazi Mehrdad,Schick Kendall J.,Horvei Paulina,Ruff Michael W.,Can Ismail,Adada Mohamad,Bezerra Evandro,Kankeu Fonkoua Lionel Aurelien,Parikh Sameer A.^ORCID,Kay Neil E.^ORCID,Sakemura Reona,Kenderian Saad S.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Cancer Research,Hematology

Link

https://www.nature.com/articles/s41375-022-01572-7.pdf

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3. Khadka RH, Sakemura R, Kenderian SS, Johnson AJ. Management of cytokine release syndrome: an update on emerging antigen-specific T cell engaging immunotherapies. Immunotherapy. 2019;11:851–7.

4. Teachey DT, Lacey SF, Shaw PA, Melenhorst JJ, Maude SL, Frey N, et al. Identification of predictive biomarkers for cytokine release syndrome after chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia. Cancer Discov. 2016;6:664–79.

5. Locke FL, Ghobadi A, Jacobson CA, Miklos DB, Lekakis LJ, Oluwole OO, et al. Long-term safety and activity of axicabtagene ciloleucel in refractory large B-cell lymphoma (ZUMA-1): a single-arm, multicentre, phase 1–2 trial. Lancet Oncol. 2019;20:31–42.

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