Thiopurine-mediated impairment of hematopoietic stem and leukemia cells in Nudt15R138C knock-in mice-Reference-Cited by-同舟云学术

Thiopurine-mediated impairment of hematopoietic stem and leukemia cells in Nudt15R138C knock-in mice

Published:2019-10-24 Issue:3 Volume:34 Page:882-894
ISSN:0887-6924
Container-title:Leukemia
language:en
Short-container-title:Leukemia

Author:

Tatsumi Goichi^ORCID,Kawahara Masahiro^ORCID,Imai Takayuki,Nishishita-Asai Ai,Nishida Atsushi,Inatomi Osamu,Yokoyama Akihiko,Kakuta Yoichi^ORCID,Kito Katsuyuki,Andoh Akira

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Cancer Research,Hematology

Link

http://www.nature.com/articles/s41375-019-0583-9.pdf

Reference43 articles.

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3. Goldberg R, Irving PM. Toxicity and response to thiopurines in patients with inflammatory bowel disease. Expert Rev Gastroenterol Hepatol. 2015;9:891–900.

4. Koren G, Ferrazini G, Sulh H, Langevin AM, Kapelushnik J, Klein J, et al. Systemic exposure to mercaptopurine as a prognostic factor in acute lymphocytic leukemia in children. N Engl J Med. 1990;323:17–21.

5. Thomas DA, O’Brien S, Cortes J, Giles FJ, Faderl S, Verstovsek S, et al. Outcome with the hyper-CVAD regimens in lymphoblastic lymphoma. Blood. 2004;104:1624–30.

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1. Nudt15-mediated inflammatory signaling contributes to divergent outcomes in leukemogenesis and hematopoiesis;Leukemia;2024-07-18

2. The frequency of NUDT15 rs116855232 and its impact on mercaptopurine-induced toxicity in Syrian children with acute lymphoblastic leukemia;Frontiers in Oncology;2024-03-18

3. Thiopurines exert harmful effects on spermatogenesis in Nudt15R138C knock-in mice;Journal of Gastroenterology;2023-12-15

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5. Loss of Nudt15 thiopurine detoxification increases direct DNA damage in hematopoietic stem cells;Scientific Reports;2023-07-24