Gene regulation in t(6;9) DEK::NUP214 Acute Myeloid Leukemia resembles that of FLT3-ITD/NPM1 Acute Myeloid Leukemia but with an altered HOX/MEIS axis-Reference-Cited by-同舟云学术

Gene regulation in t(6;9) DEK::NUP214 Acute Myeloid Leukemia resembles that of FLT3-ITD/NPM1 Acute Myeloid Leukemia but with an altered HOX/MEIS axis

Published:2024-01-04 Issue:2 Volume:38 Page:403-407
ISSN:0887-6924
Container-title:Leukemia
language:en
Short-container-title:Leukemia

Author:

Potluri Sandeep^ORCID,Kellaway Sophie G.^ORCID,Coleman Daniel J. L.^ORCID,Keane Peter^ORCID,Imperato Maria Rosaria,Assi Salam A.,Cockerill Peter N.^ORCID,Bonifer Constanze^ORCID

Funder

Bloodwise

RCUK | Medical Research Council

Publisher

Springer Science and Business Media LLC

Link

https://www.nature.com/articles/s41375-023-02118-1.pdf

Reference15 articles.

1. Slovak ML, Gundacker H, Bloomfield CD, Dewald G, Appelbaum FR, Larson RA, et al. A retrospective study of 69 patients with t(6;9)(p23;q34) AML emphasizes the need for a prospective, multicenter initiative for rare ‘poor prognosis’ myeloid malignancies. Leukemia. 2006;20:1295–7. https://doi.org/10.1038/sj.leu.2404233.

2. Assi SA, Imperato MR, Coleman DJL, Pickin A, Potluri S, Ptasinska A, et al. Subtype-specific regulatory network rewiring in acute myeloid leukemia. Nat Genet. 2019;51:151–62. https://doi.org/10.1038/s41588-018-0270-1.

3. Hollink IH, van den Heuvel-Eibrink MM, Arentsen-Peters ST, Pratcorona M, Abbas S, Kuipers JE, et al. NUP98/NSD1 characterizes a novel poor prognostic group in acute myeloid leukemia with a distinct HOX gene expression pattern. Blood. 2011;118:3645–56. https://doi.org/10.1182/blood-2011-04-346643.

4. Sandahl JD, Coenen EA, Forestier E, Harbott J, Johansson B, Kerndrup G, et al. t(6;9)(p22;q34)/DEK-NUP214-rearranged pediatric myeloid leukemia: an international study of 62 patients. Haematologica. 2014;99:865–72. https://doi.org/10.3324/haematol.2013.098517.

5. Mendes A, Fahrenkrog B. NUP214 in Leukemia: It’s More than Transport. Cells. 2019;8:76. https://doi.org/10.3390/cells8010076.