Targeting quiescent leukemic stem cells using second generation autophagy inhibitors-Reference-Cited by-同舟云学术

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Targeting quiescent leukemic stem cells using second generation autophagy inhibitors

Published:2018-09-05 Issue:4 Volume:33 Page:981-994
ISSN:0887-6924
Container-title:Leukemia
language:en
Short-container-title:Leukemia

Author:

Baquero Pablo,Dawson Amy,Mukhopadhyay Arunima,Kuntz Elodie M.,Mitchell Rebecca,Olivares Orianne,Ianniciello Angela,Scott Mary T.,Dunn Karen,Nicastri Michael C.,Winkler Jeffrey D.,Michie Alison M.^ORCID,Ryan Kevin M.,Halsey Christina,Gottlieb Eyal,Keaney Erin P.,Murphy Leon O.,Amaravadi Ravi K.,Holyoake Tessa L.,Helgason G. Vignir^ORCID

Funder

Kay Kendall Leukaemia Fund (KKLF)

SULSA | Scottish Universities Life Sciences Alliance

Medical Research Council (MRC)

Cancer Research UK (CRUK)

Bloodwise Specialist Programme (14033) the Howat Foundation Friends of Paul O'Gorman

Lady Tata Memorial Trust

Leuka: John Goldman Fellowship The Howat Foundation Friends of Paul O'Gorman Leukaemia Research Centre

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Cancer Research,Hematology

Link

http://www.nature.com/articles/s41375-018-0252-4.pdf

Reference43 articles.

1. Druker BJ, Guilhot F, O’Brien SG, Gathmann I, Kantarjian H, Gattermann N, et al. 5-year follow-up of patients receiving imatinib for chronic myeloid leukemia. N Engl J Med. 2006;355:2408–17.

2. Holyoake TL, Vetrie D. The chronic myeloid leukemia stem cell: stemming the tide of persistence. Blood. 2017;129:1595–606.

3. Corbin AS, Agarwal A, Loriaux M, Cortes J, Deininger MW, Druker BJ. Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity. J Clin Invest. 2011;121:396–409.

4. Hamilton A, Helgason GV, Schemionek M, Zhang B, Myssina S, Allan EK, et al. Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival. Blood. 2012;119:1501–10.

5. Holyoake TL, Helgason GV. Do we need more drugs for chronic myeloid leukemia? Immunol Rev. 2015;263:106–23.

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