Adult T-cell acute lymphoblastic leukemias with IL7R pathway mutations are slow-responders who do not benefit from allogeneic stem-cell transplantation-Reference-Cited by-同舟云学术

Adult T-cell acute lymphoblastic leukemias with IL7R pathway mutations are slow-responders who do not benefit from allogeneic stem-cell transplantation

Published:2020-01-28 Issue:7 Volume:34 Page:1730-1740
ISSN:0887-6924
Container-title:Leukemia
language:en
Short-container-title:Leukemia

Author:

Kim Rathana, ,Boissel Nicolas,Touzart Aurore,Leguay Thibaut,Thonier Florian,Thomas Xavier,Raffoux Emmanuel,Huguet Françoise,Villarese Patrick,Fourrage Cécile,Passini Loïc,Hunault Mathilde,Lepretre Stéphane,Chevallier Patrice,Braun Thorsten,Lhéritier Véronique,Chantepie Sylvain,Maury Sébastien,Escoffre Martine,Tavernier Emmanuelle,Chalandon Yves^ORCID,Graux Carlos,Macintyre Elizabeth,Ifrah Norbert,Asnafi Vahid,Dombret Hervé,Lhermitte Ludovic^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Cancer Research,Hematology

Link

http://www.nature.com/articles/s41375-019-0685-4.pdf

Reference50 articles.

1. Aifantis I, Raetz E, Buonamici S. Molecular pathogenesis of T-cell leukaemia and lymphoma. Nat Rev Immunol. 2008;8:380–90.

2. Van Vlierberghe P, Ferrando A. The molecular basis of T cell acute lymphoblastic leukemia. J Clin Investig. 2012;122:3398–406.

3. Girardi T, Vicente C, Cools J, De Keersmaecker K. The genetics and molecular biology of T-ALL. Blood. 2017;129:1113–23.

4. Goldstone AH, Richards SM, Lazarus HM, Tallman MS, Buck G, Fielding AK, et al. In adults with standard-risk acute lymphoblastic leukemia, the greatest benefit is achieved from a matched sibling allogeneic transplantation in first complete remission, and an autologous transplantation is less effective than conventional consolidation/maintenance chemotherapy in all patients: final results of the International ALL Trial (MRC UKALL XII/ECOG E2993). Blood. 2008;111:1827–33.

5. Gökbuget N, Kneba M, Raff T, Trautmann H, Bartram C-R, Arnold R, et al. Adult patients with acute lymphoblastic leukemia and molecular failure display a poor prognosis and are candidates for stem cell transplantation and targeted therapies. Blood. 2012;120:1868–76.

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