DNA-thioguanine concentration and relapse risk in children and young adults with acute lymphoblastic leukemia: an IPD meta-analysis-Reference-Cited by-同舟云学术

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DNA-thioguanine concentration and relapse risk in children and young adults with acute lymphoblastic leukemia: an IPD meta-analysis

Published:2021-06-26 Issue:1 Volume:36 Page:33-41
ISSN:0887-6924
Container-title:Leukemia
language:en
Short-container-title:Leukemia

Author:

Toksvang Linea N.^ORCID,Grell Kathrine,Nersting Jacob,Degn Matilda,Nielsen Stine N.,Abrahamsson Jonas,Lund Bendik,Kanerva Jukka,Jónsson Ólafur G.,Lepik Kristi,Vaitkevičienė Goda,Griškevičius Laimonas,Quist-Paulsen Petter,Vora Ajay,Moorman Anthony V.,Murdy Daniel,Zimmermann Martin,Möricke Anja,Bostrom Bruce^ORCID,Joshi Jaitri^ORCID,Hjalgrim Lisa L.,Dalhoff Kim P.,Als-Nielsen Bodil,Schmiegelow Kjeld^ORCID

Funder

Kræftens Bekæmpelse

Barncancerfonden

Ingeniør Otto Christensens Fond

Nordic Cancer Union United Kingdom Medical Research Council

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Cancer Research,Hematology

Link

https://www.nature.com/articles/s41375-021-01182-9.pdf

Reference26 articles.

1. Schmiegelow K, Nielsen SN, Frandsen TL, Nersting J. Mercaptopurine/Methotrexate maintenance therapy of childhood acute lymphoblastic leukemia: clinical facts and fiction. J Pediatr Hematol Oncol. 2014;36:503–17.

2. Nielsen SN, Grell K, Nersting J, Frandsen TL, Hjalgrim LL, Schmiegelow K. Measures of 6-mercaptopurine and methotrexate maintenance therapy intensity in childhood acute lymphoblastic leukemia. Cancer Chemother Pharm. 2016;78:983–94.

3. Swann PF, Waters TR, Moulton DC, Xu YZ, Zheng Q, Edwards M, et al. Role of postreplicative DNA mismatch repair in the cytotoxic action of thioguanine. Science. 1996;273:1109–11.

4. Gefen N, Brkic G, Galron D, Priel E, Ozer J, Benharroch D, et al. Acquired resistance to 6-thioguanine in melanoma cells involves the repair enzyme O6-methylguanine-DNA methyltransferase (MGMT). Cancer Biol Ther. 2010;9:49–55.

5. Karran P, Attard N. Thiopurines in current medical practice: molecular mechanisms and contributions to therapy-related cancer. Nat Rev Cancer. 2008;8:24–36.

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1. Modulation of mercaptopurine intestinal toxicity and pharmacokinetics by gut microbiota;Biomedicine & Pharmacotherapy;2024-08

2. Innovating Thiopurine Therapeutic Drug Monitoring: A Systematic Review and Meta-Analysis on DNA-Thioguanine Nucleotides (DNA-TG) as an Inclusive Biomarker in Thiopurine Therapy;Clinical Pharmacokinetics;2024-07-20

3. Erythrocyte-incorporated 6-mercaptopurine metabolite levels are not affected by recent drug administration during maintenance therapy for childhood acute lymphoblastic leukemia;EJC Paediatric Oncology;2023-12

4. Pharmacokinetic–pharmacodynamic modeling of maintenance therapy for childhood acute lymphoblastic leukemia;Scientific Reports;2023-07-20

5. Thiopurine Methyltransferase Intermediate Metabolizer Status and Thiopurine‐Associated Toxicity During Maintenance Therapy in Childhood Acute Lymphoblastic Leukemia;Clinical Pharmacology & Therapeutics;2023-04-03

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