Preclinical evaluation of the selective small-molecule UBA1 inhibitor, TAK-243, in acute myeloid leukemia-Reference-Cited by-同舟云学术

Preclinical evaluation of the selective small-molecule UBA1 inhibitor, TAK-243, in acute myeloid leukemia

Published:2018-06-08 Issue:1 Volume:33 Page:37-51
ISSN:0887-6924
Container-title:Leukemia
language:en
Short-container-title:Leukemia

Author:

Barghout Samir H.^ORCID,Patel Parasvi S.,Wang Xiaoming,Xu G. Wei,Kavanagh Simon^ORCID,Halgas Ondrej,Zarabi Sara F.,Gronda Marcela,Hurren Rose,Jeyaraju Danny V.,MacLean Neil,Brennan Shawn,Hyer Marc L.,Berger Allison,Traore Tary,Milhollen Michael,Smith Adam C.,Minden Mark D.,Pai Emil F.,Hakem Razq,Schimmer Aaron D.

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Cancer Research,Hematology

Link

http://www.nature.com/articles/s41375-018-0167-0.pdf

Reference46 articles.

1. Stone RM, Mandrekar SJ, Sanford BL, Laumann K, Geyer S, Bloomfield CD, et al. Midostaurin plus chemotherapy for acute myeloid leukemia with a FLT3 mutation. N Engl J Med. 2017;377:454–64.

2. Mitch Leslie, Positive first trial of enasidenib for AML. Cancer Discov. 2017; 7: OF1.

3. Ferrara F, Schiffer CA. Acute myeloid leukaemia in adults. Lancet. 2013;381:484–95.

4. Dohner H, Weisdorf DJ, Bloomfield CD. Acute myeloid leukemia. N Engl J Med. 2015;373:1136–52.

5. Khwaja A, Bjorkholm M, Gale RE, Levine RL, Jordan CT, Ehninger G, et al. Acute myeloid leukaemia. Nat Rev Dis Prim. 2016;2:16010.

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