High expression of an intragenic long noncoding RNA misinterpreted as high FTO oncogene expression in NPM1 mutant acute myeloid leukemia
Author:
Funder
Stichting Kinderen Kankervrij
Publisher
Springer Science and Business Media LLC
Subject
Oncology,Cancer Research,Hematology
Link
https://www.nature.com/articles/s41375-023-01844-w.pdf
Reference15 articles.
1. Li Z, Weng H, Su R, Weng X, Zuo Z, Li C, et al. FTO plays an oncogenic role in acute myeloid leukemia as a N(6)-methyladenosine RNA demethylase. Cancer Cell. 2017;31:127–41.
2. Lan N, Lu Y, Zhang Y, Pu S, Xi H, Nie X, et al. FTO—a common genetic basis for obesity and cancer. Front Genet. 2020;11:559138.
3. Huang Y, Su R, Sheng Y, Dong L, Dong Z, Xu H, et al. Small-molecule targeting of oncogenic FTO demethylase in acute myeloid leukemia. Cancer Cell. 2019;35:677–91.e10.
4. Qing Y, Su R, Chen J. Targeting FTO for cancer therapy and more. Aging. 2021;13:19080–2.
5. Xiao Q, Lei L, Ren J, Peng M, Jing Y, Jiang X, et al. Mutant NPM1-regulated FTO-mediated m(6)A demethylation promotes leukemic cell survival via PDGFRB/ERK signaling axis. Front Oncol. 2022;12:817584.
Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. A novel AML1-ETO/FTO positive feedback loop promotes leukemogenesis and Ara-C resistance via stabilizing IGFBP2 in t(8;21) acute myeloid leukemia;Experimental Hematology & Oncology;2024-01-24
2. Differentiation block in acute myeloid leukemia regulated by intronic sequences of FTO;iScience;2023-08
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