Early and sensitive detection of PML-A216V mutation by droplet digital PCR in ATO-resistant acute promyelocytic leukemia
Author:
Publisher
Springer Science and Business Media LLC
Subject
Oncology,Cancer Research,Hematology
Link
http://www.nature.com/articles/s41375-018-0298-3.pdf
Reference6 articles.
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2. Burnett AK, Russell NH, Hills RK, Bowen D, Kell J, Knapper S, et al. Arsenic trioxide and all-trans retinoic acid treatment for acute promyelocytic leukaemia in all risk groups (AML17): results of a randomised, controlled, phase 3 trial. Lancet Oncol. 2015;16:1295–305.
3. Iaccarino L, Ottone T, Divona M, Cicconi L, Cairoli R, Voso MT, et al. Mutations affecting both the rearranged and the unrearranged PML alleles in refractory acute promyelocytic leukaemia. Br J Haematol. 2016;172:909–13.
4. Zhu H-H, Qin Y-Z, Huang X-J. Resistance to arsenic therapy in acute promyelocytic leukemia. N Engl J Med. 2014;370:1864–6.
5. Lehmann-Che J, Bally C, de Thé H. Resistance to therapy in acute promyelocytic leukemia. N Engl J Med. 2014;371:1170–2.
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