CD133-directed CAR T-cells for MLL leukemia: on-target, off-tumor myeloablative toxicity-Reference-Cited by-同舟云学术

CD133-directed CAR T-cells for MLL leukemia: on-target, off-tumor myeloablative toxicity

Published:2019-02-18 Issue:8 Volume:33 Page:2090-2125
ISSN:0887-6924
Container-title:Leukemia
language:en
Short-container-title:Leukemia

Author:

Bueno Clara,Velasco-Hernandez Talia,Gutiérrez-Agüera Francisco,Zanetti Samanta Romina,Baroni Matteo L.,Sánchez-Martínez Diego,Molina Oscar,Closa Adria,Agraz-Doblás Antonio,Marín Pedro,Eyras Eduardo,Varela Ignacio^ORCID,Menéndez Pablo

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Cancer Research,Hematology

Link

http://www.nature.com/articles/s41375-019-0418-8.pdf

Reference19 articles.

1. Maude, SL, Laetsch TW, Buechner J, Rives S, Boyer M, Bittencourt H, et al. Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia. N Engl J Med. 2018;378:439–48.

2. Ghorashian S, Amrolia P, Veys P. Open access? Widening access to chimeric antigen receptor (CAR) therapy for ALL. Exp Hematol. 2018;66:5–16.

3. Gardner R, Wu D, Cherian S, Fang M, Hanafi LA, Finney O, et al. Acquisition of a CD19-negative myeloid phenotype allows immune escape of MLL-rearranged B-ALL from CD19 CAR-T-cell therapy. Blood. 2016;127:2406–10.

4. Sotillo E, Barrett DM, Black KL, Bagashev A, Oldridge D, Wu G, et al. Convergence of acquired mutations and alternative splicing of CD19 enables resistance to CART-19 immunotherapy. Cancer Discov. 2015;5:1282–95.

5. Sanjuan-Pla A, Bueno C, Prieto C, Acha P, Stam RW, Marschalek R, et al. Revisiting the biology of infant t(4;11)/MLL-AF4 + B-cell acute lymphoblastic leukemia. Blood. 2015;126:2676–85.

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