The obesity-associated SNPs in intron 1 of the FTO gene affect primary transcript levels
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics(clinical),Genetics
Link
http://www.nature.com/articles/ejhg201071.pdf
Reference20 articles.
1. Frayling TM, Timpson NJ, Weedon NM et al: A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007; 316: 889–892.
2. Dina C, Meyre D, Gallina S et al: Variation in FTO contributes to childhood obesity and severe adult obesity. Nat Genet 2007; 39: 724–726.
3. Gerken T, Girard ChA, Tung YL et al: The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. Science 2007; 318: 1469–1474.
4. Boissel S, Reish O, Proulx K et al: Loss-of-Function mutation in the dioxygenase-encoding FTO gene causes severe growth retardation and multiple malformations. Am J Hum Genet 2009; 85: 106–111.
5. Meyre D, Proulx K, Kawagoe-Takaki H et al: Prevalence of loss of function FTO mutations in lean and obese individuals. Diabetes 2010; 59: 311–318.
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