In vivo affinity maturation of mouse B cells reprogrammed to express human antibodies
Author:
Funder
U.S. Department of Health & Human Services | National Institutes of Health
Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s41551-024-01179-6.pdf
Reference63 articles.
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3. Shih, T. A., Meffre, E., Roederer, M. & Nussenzweig, M. C. Role of BCR affinity in T cell–dependent antibody responses in vivo. Nat. Immunol. 3, 570–575 (2002).
4. Wardemann, H. et al. Predominant autoantibody production by early human B cell precursors. Science 301, 1374–1377 (2003).
5. Jarasch, A. et al. Developability assessment during the selection of novel therapeutic antibodies. J. Pharm. Sci. 104, 1885–1898 (2015).
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