EBNA1-targeted probe for the imaging and growth inhibition of tumours associated with the Epstein

EBNA1-targeted probe for the imaging and growth inhibition of tumours associated with the Epstein–Barr virus

Published:2017-03-13 Issue:4 Volume:1 Page:
ISSN:2157-846X
Container-title:Nature Biomedical Engineering
language:en
Short-container-title:Nat Biomed Eng

Author:

Jiang Lijun,Lan Rongfeng^ORCID,Huang Tao,Chan Chi-Fai,Li Hongguang,Lear Sam,Zong Jingyi,Wong Wing-Yan,Muk-Lan Lee Magnolia,Dow Chan Brandon,Chan Wai-Lun,Lo Wai-Sum,Mak Nai-Ki,Li Lung Maria,Lok Lung Hong,Wah Tsao Sai,Taylor Graham S.,Bian Zhao-Xiang,Tai William C. S.,Law Ga-Lai,Wong Wing-Tak,Cobb Steven L.,Wong Ka-Leung

Publisher

Springer Science and Business Media LLC

Subject

Computer Science Applications,Biomedical Engineering,Medicine (miscellaneous),Bioengineering,Biotechnology

Link

http://www.nature.com/articles/s41551-017-0042.pdf

Reference24 articles.

1. Cohen, J. I. Epstein–Barr virus infection. N. Eng. J. Med. 343, 481–492 (2000).

2. Young, L. S. & Rickinson, A. B. Epstein–Barr virus: 40 years on. Nat. Rev. Cancer 4, 757–768 (2004).

3. Thorley-Lawson, D. A. Epstein–Barr virus: exploiting the immune system. Nat. Rev. Immunol. 1, 75–82 (2001).

4. Paludan, S. R., Bowie A. G., Horan K. A. & Fitzgerald K. A. Recognition of herpesviruses by the innate immune system. Nat. Rev. Immunol. 11, 143–154 (2011).

5. Wood, V. H. J. et al. Epstein–Barr virus-encoded EBNA1 regulates cellular gene transcription and modulates the STAT1 and TGFb signalling pathways. Oncogene 26, 4135–4147 (2007).

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