Reduction of the therapeutic dose of silencing RNA by packaging it in extracellular vesicles via a pre-microRNA backbone-Reference-Cited by-同舟云学术

Reduction of the therapeutic dose of silencing RNA by packaging it in extracellular vesicles via a pre-microRNA backbone

Published:2020-01 Issue:1 Volume:4 Page:52-68
ISSN:2157-846X
Container-title:Nature Biomedical Engineering
language:en
Short-container-title:Nat Biomed Eng

Author:

Reshke Ryan,Taylor James A.,Savard Alexandre,Guo Huishan,Rhym Luke H.,Kowalski Piotr S.,Trung My Tran,Campbell Charles,Little Wheaton,Anderson Daniel G.,Gibbings Derrick^ORCID

Funder

Juvenile Diabetes Research Foundation

Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada

Gouvernement du Canada | Instituts de Recherche en Santé du Canada | CIHR Skin Research Training Centre

Ontario Centres of Excellence

ALS Society of Canada

Publisher

Springer Science and Business Media LLC

Subject

Computer Science Applications,Biomedical Engineering,Medicine (miscellaneous),Bioengineering,Biotechnology

Link

http://www.nature.com/articles/s41551-019-0502-4.pdf

Reference51 articles.

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3. Coelho, T. et al. Safety and efficacy of RNAi therapy for transthyretin amyloidosis. N. Engl. J. Med. 369, 819–829 (2013).

4. Whitehead, Ka, Langer, R. & Anderson, D. G. Knocking down barriers: advances in siRNA delivery. Nat. Rev. Drug Discov. 8, 129–138 (2009).

5. Kanasty, R., Dorkin, J. R., Vegas, A. & Anderson, D. Delivery materials for siRNA therapeutics. Nat. Mater. 12, 967–977 (2013).

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