Chemical combination effects predict connectivity in biological systems

Author:

Lehár Joseph12,Zimmermann Grant R1,Krueger Andrew S2,Molnar Raymond A1,Ledell Jebediah T1,Heilbut Adrian M1,Short Glenn F1,Giusti Leanne C1,Nolan Garry P1,Magid Omar A1,Lee Margaret S1,Borisy Alexis A1,Stockwell Brent R3,Keith Curtis T1

Affiliation:

1. CombinatoRx, Incorporated Cambridge MA USA

2. Bioinformatics and Biomedical Engineering, Boston University Boston MA USA

3. Department of Biological Sciences and Department of Chemistry, Fairchild Center, Columbia University New York NY USA

Publisher

EMBO

Subject

Applied Mathematics,Computational Theory and Mathematics,General Agricultural and Biological Sciences,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Information Systems

Reference62 articles.

1. A System of Models for the Action of Drugs Applied Singly or Jointly to Biological Organisms

2. The role of transforming growth factor alpha in determining growth factor independence;Awwad RA;Cancer Res,2003

3. The expected effect of a combination of agents: the general solution

4. What is synergy?;Berenbaum MC;Pharmacol Rev,1989

5. Alendronate Is a Specific, Nanomolar Inhibitor of Farnesyl Diphosphate Synthase

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3