Sex differences in molecular neuroscience: from fruit flies to humans
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Neuroscience
Link
http://www.nature.com/articles/nrn2754.pdf
Reference118 articles.
1. Fitzpatrick, J. M. et al. An oligonucleotide microarray for transcriptome analysis of Schistosoma mansoni and its application/use to investigate gender-associated gene expression. Mol. Biochem. Parasitol. 141, 1–13 (2005).
2. Jin, W. et al. The contributions of sex, genotype and age to transcriptional variance in Drosophila melanogaster. Nature Genet. 29, 389–395 (2001). A genome-wide analysis of sex bias in gene expression in flies, demonstrating that around one-half of the transcriptome differs significantly between the two sexes and that adult age has remarkably little effect on transcriptional variance.
3. Santos, E. M. et al. Molecular basis of sex and reproductive status in breeding zebrafish. Physiol. Genomics 30, 111–122 (2007).
4. Yang, X. et al. Tissue-specific expression and regulation of sexually dimorphic genes in mice. Genome Res. 16, 995–1004 (2006).
5. Reinius, B. et al. An evolutionarily conserved sexual signature in the primate brain. PLoS Genet. 4, e1000100 (2008). This article demonstrates that some human sex-specific gene expression patterns are conserved in the brains of other primates. Conservation across species indicates that these patterns may underlie some genetic differences between the sexes.
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