RKTG inhibits angiogenesis by suppressing MAPK-mediated autocrine VEGF signaling and is downregulated in clear-cell renal cell carcinoma-Reference-Cited by-同舟云学术

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RKTG inhibits angiogenesis by suppressing MAPK-mediated autocrine VEGF signaling and is downregulated in clear-cell renal cell carcinoma

Published:2010-07-05 Issue:39 Volume:29 Page:5404-5415
ISSN:0950-9232
Container-title:Oncogene
language:en
Short-container-title:Oncogene

Author:

Zhang Y,Jiang X,Qin X,Ye D,Yi Z,Liu M,Bai O,Liu W,Xie X,Wang Z,Fang J,Chen Y

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Link

http://www.nature.com/articles/onc2010270.pdf

Reference39 articles.

1. Alavi A, Hood JD, Frausto R, Stupack DG, Cheresh DA . (2003). Role of Raf in vascular protection from distinct apoptotic stimuli. Science 301: 94–96.

2. Arany Z, Huang LE, Eckner R, Bhattacharya S, Jiang C, Goldberg MA et al. (1996). An essential role for p300/CBP in the cellular response to hypoxia. Proc Natl Acad Sci USA 93: 12969–12973.

3. Dougher M, Terman BI . (1999). Autophosphorylation of KDR in the kinase domain is required for maximal VEGF-stimulated kinase activity and receptor internalization. Oncogene 18: 1619–1627.

4. Ema M, Hirota K, Mimura J, Abe H, Yodoi J, Sogawa K et al. (1999). Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300. EMBO J 18: 1905–1914.

5. Escudier B, Eisen T, Stadler WM, Szczylik C, Oudard S, Siebels M et al.. (2007). Sorafenib in advanced clear-cell renal-cell carcinoma. N Engl J Med 356: 125–134.

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