Opposite functions of HIF-α isoforms in VEGF induction by TGF-β1 under non-hypoxic conditions

Author:

Chae K S,Kang M J,Lee J H,Ryu B K,Lee M G,Her N G,Ha T K,Han J,Kim Y K,Chi S G

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Reference55 articles.

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3. Blancher C, Moore JW, Talks KL, Houlbrook S, Harris AL . (2000). Relationship of hypoxia-inducible factor (HIF)-1α and HIF-2α expression to vascular endothelial growth factor induction and hypoxia survival in human breast cancer cell lines. Cancer Res 60: 7106–7113.

4. Boddy JL, Fox SB, Han C, Campo L, Turley H, Kanga S et al. (2005). The androgen receptor is significantly associated with vascular endothelial growth factor and hypoxia sensing via hypoxia-inducible factors HIF-1α, HIF-2α, and the prolyl hydroxylases in human prostate cancer. Clin Cancer Res 11: 7658–7663.

5. Brown JM, Wilson WR . (2004). Exploiting tumour hypoxia in cancer treatment. Nat Rev Cancer 4: 437–447.

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