Directed Evolution of a Novel Adeno-associated Virus (AAV) Vector That Crosses the Seizure-compromised Blood–Brain Barrier (BBB)-Reference-Cited by-同舟云学术

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Directed Evolution of a Novel Adeno-associated Virus (AAV) Vector That Crosses the Seizure-compromised Blood–Brain Barrier (BBB)

Published:2010-03 Issue:3 Volume:18 Page:570-578
ISSN:1525-0016
Container-title:Molecular Therapy
language:en
Short-container-title:Molecular Therapy

Author:

Gray Steven J,Blake Bonita L,Criswell Hugh E,Nicolson Sarah C,Samulski R Jude,McCown Thomas J

Funder

National Institute of Neurological Disorders and Stroke

International Rett Syndrome Foundation

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference29 articles.

1. Attenuation of seizures and neuronal death by adeno-associated virus vector galanin expression and secretion;Haberman;Nat Med,2003

2. Adeno-associated virus-mediated expression and constitutive secretion of galanin suppresses limbic seizure activity in vivo;McCown;Mol Ther,2006

3. Anticonvulsant and antiepileptic effects mediated by adeno-associated virus vector neuropeptide Y expression in the rat hippocampus;Richichi;J Neurosci,2004

4. Viral vector gene therapy for epilepsy;Foti,2009

5. Directed evolution of adeno-associated virus yields enhanced gene delivery vectors;Maheshri;Nat Biotechnol,2006

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