Mechanism of Reduction in Titers From Lentivirus Vectors Carrying Large Inserts in the 3′LTR-Reference-Cited by-同舟云学术

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Mechanism of Reduction in Titers From Lentivirus Vectors Carrying Large Inserts in the 3′LTR

Published:2009-09 Issue:9 Volume:17 Page:1527-1536
ISSN:1525-0016
Container-title:Molecular Therapy
language:en
Short-container-title:Molecular Therapy

Author:

Urbinati Fabrizia,Arumugam Paritha,Higashimoto Tomoyasu,Perumbeti Anil,Mitts Kyle,Xia Ping,Malik Punam

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference50 articles.

1. A novel murine model of Cooley anemia and its rescue by lentiviral-mediated human β-globin gene transfer;Rivella;Blood,2003

2. The degree of phenotypic correction of murine β-thalassemia intermedia following lentiviral-mediated transfer of a human gamma-globin gene is influenced by chromosomal position effects and vector copy number;Persons;Blood,2003

3. Permanent and panerythroid correction of murine β thalassemia by multiple lentiviral integration in hematopoietic stem cells;Imren;Proc Natl Acad Sci USA,2002

4. Cell-culture assays reveal the importance of retroviral vector design for insertional genotoxicity;Modlich;Blood,2006

5. Gene therapy: X-SCID transgene leukaemogenicity;Thrasher;Nature,2006

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