Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche-Reference-Cited by-同舟云学术

Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche

Published:2014-12-01 Issue:1 Volume:21 Page:62-70
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Davis Hayley,Irshad Shazia,Bansal Mukesh^ORCID,Rafferty Hannah,Boitsova Tatjana,Bardella Chiara,Jaeger Emma,Lewis Annabelle,Freeman-Mills Luke,Giner Francesc C^ORCID,Rodenas-Cuadrado Pedro,Mallappa Sreelakshmi,Clark Susan,Thomas Huw,Jeffery Rosemary,Poulsom Richard,Rodriguez-Justo Manuel,Novelli Marco,Chetty Runjan,Silver Andrew,Sansom Owen J,Greten Florian R,Wang Lai Mun,East James E,Tomlinson Ian^ORCID,Leedham Simon J

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm.3750.pdf

Reference42 articles.

1. Barker, N. et al. Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature 449, 1003–1007 (2007).

2. van den Brink, G.R. & Offerhaus, G. The morphogenetic code and colon cancer development. Cancer Cell 11, 109–117 (2007).

3. Hardwick, J.C. et al. Bone morphogenetic protein 2 is expressed by, and acts upon, mature epithelial cells in the colon. Gastroenterology 126, 111–121 (2004).

4. Scoville, D.H., Sato, T., He, X. & Li, L. Current view: intestinal stem cells and signaling. Gastroenterology 134, 849–864 (2008).

5. Fearon, E.R. & Vogelstein, B. A genetic model for colorectal tumorigenesis. Cell 61, 759–767 (1990).

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