A conformational change within the WAVE2 complex regulates its degradation following cellular activation
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep44863.pdf
Reference59 articles.
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2. Hahne, P., Sechi, A., Benesch, S. & Small, J. V. Scar/WAVE is localised at the tips of protruding lamellipodia in living cells. FEBS Lett. 492, 215–220 (2001).
3. Law, A. L . et al. Lamellipodin and the Scar/WAVE complex cooperate to promote cell migration in vivo . J Cell Biol (2013).
4. Biyasheva, A., Svitkina, T., Kunda, P., Baum, B. & Borisy, G. Cascade pathway of filopodia formation downstream of SCAR. J Cell Sci. 117, 837–848 (2004).
5. Suetsugu, S., Miki, H. & Takenawa, T. Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complex. Biochem Biophys Res Commun. 260, 296–302 (1999).
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