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General rules for functional microRNA targeting

Published:2016-10-24 Issue:12 Volume:48 Page:1517-1526
ISSN:1061-4036
Container-title:Nature Genetics
language:en
Short-container-title:Nat Genet

Author:

Kim Doyeon,Sung You Me,Park Jinman,Kim Sukjun,Kim Jongkyu,Park Junhee,Ha Haeok,Bae Jung Yoon,Kim SoHui,Baek Daehyun

Publisher

Springer Science and Business Media LLC

Subject

Genetics

Link

http://www.nature.com/articles/ng.3694.pdf

Reference51 articles.

1. Friedman, R.C., Farh, K.K.H., Burge, C.B. & Bartel, D.P. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res. 19, 92–105 (2009).

2. Bartel, D.P. MicroRNAs: target recognition and regulatory functions. Cell 136, 215–233 (2009).

3. Selbach, M. et al. Widespread changes in protein synthesis induced by microRNAs. Nature 455, 58–63 (2008).

4. Melo, S.A. & Kalluri, R. miR-29b moulds the tumour microenvironment to repress metastasis. Nat. Cell Biol. 15, 139–140 (2013).

5. Kasinski, A.L. & Slack, F.J. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy. Nat. Rev. Cancer 11, 849–864 (2011).

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